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The 5-HT4 partial agonist, tegaserod, improve abdominal discomfort/pain and normalize altered bowel manoeuvre in irritable bowel syndrome (IBS). Am J Gastroenterol 1999; 94:266.&lt;/p&gt;&lt;br /&gt;&lt;p&gt;10. Novick J, et al. A randomized, double-blind, placebocontrolled testing of tegaserod in womanly patients suffering from irritable bowel syndrome with constipation.Aliment Pharmacol Ther 2002; 16:1877-1888.&lt;/p&gt;&lt;br /&gt;&lt;p&gt;11. Kellow J, et al. An Asia-Pacific, lookalike unsighted, placebo controlled, randomised study to balance the efficacy, refuge, and tolerability of tegaserod in patients with irritable bowel syndrome. Gut 2003; 52:671-676.&lt;/p&gt;&lt;br /&gt;&lt;p&gt;12. Nyhlin H, et al. A double-blind, placebo-controlled, randomized study to evaluate the efficacy, safety and tolerability of tegaserod in patients with irritable bowel syndrome. 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